{"id":30382,"date":"2026-04-05T10:15:00","date_gmt":"2026-04-05T15:15:00","guid":{"rendered":"https:\/\/www.ecoticias.com\/en\/?p=30382"},"modified":"2026-04-03T21:19:36","modified_gmt":"2026-04-04T02:19:36","slug":"a-5000-year-old-bacterium-awakens-from-the-ice-in-a-cave-in-romania-revealing-something-disturbing-it-was-already-resistant-to-antibiotics-still-used-today-to-treat-serious-infections","status":"publish","type":"post","link":"https:\/\/www.ecoticias.com\/en\/a-5000-year-old-bacterium-awakens-from-the-ice-in-a-cave-in-romania-revealing-something-disturbing-it-was-already-resistant-to-antibiotics-still-used-today-to-treat-serious-infections\/30382\/","title":{"rendered":"A 5,000-year-old bacterium awakens from the ice in a cave in Romania, revealing something disturbing: it was already resistant to antibiotics still used today to treat serious infections"},"content":{"rendered":"\n<p>What happens when a microbe from 5,000 years ago meets some of the strongest drugs on today\u2019s hospital shelves? In an underground glacier in Sc\u0103ri\u0219oara Ice Cave, scientists have just found out, and the answer is unsettling as well as hopeful.<\/p>\n\n\n\n<p>A team from the Romanian Academy has \u201cwoken up\u201d a cold-loving bacterium called <a href=\"https:\/\/www.frontiersin.org\/news\/2026\/02\/17\/bacteria-ancient-underground-ice-cave-resistant-antibiotics\" target=\"_blank\" rel=\"noopener\">Psychrobacter SC65A.3<\/a> from ice that formed around five millennia ago. <\/p>\n\n\n\n<div class=\"gb-element-a00da4e5\">\n<div><div class=\"gb-looper-46613eed\">\n<div class=\"gb-loop-item gb-loop-item-a8390598 post-30158 post type-post status-publish format-standard has-post-thumbnail hentry category-science resize-featured-image\">\n<h3 class=\"gb-text gb-text-24a51617\">Read More: <a href=\"https:\/\/www.ecoticias.com\/en\/nasa-explores-the-surface-of-mars-and-finds-traces-of-ice-sheets-dating-back-3-6-billion-years\/30158\/\">NASA explores the surface of Mars and finds traces of \u201cice sheets\u201d dating back 3.6 billion years<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p>In lab tests, this tiny survivor turned out to be resistant to 10 of 28 modern antibiotics that doctors routinely use for serious infections in the lungs, skin, blood, urinary tract, and reproductive system.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Scientists drilled deep into an ancient ice cave<\/h2>\n\n\n\n<p>To reach it, researchers drilled a 25 meter ice core from the cave\u2019s Great Hall, a frozen archive that spans about 13,000 years of <a href=\"https:\/\/www.ecoticias.com\/en\/scientists-hidden-seasonal-cycle-algae\/21593\/\">climate<\/a> and microbial history. From the 5,000 year level, they isolated SC65A.3, sequenced its genome, and mapped the genes that help it cope with bitter cold and low nutrients while also standing up to today\u2019s medicines.<\/p>\n\n\n\n<p>When they challenged the bacterium with antibiotics used in clinics, SC65A.3 resisted 10 drugs across eight different classes, including rifampicin, vancomycin, ciprofloxacin, trimethoprim, clindamycin, and metronidazole. <\/p>\n\n\n\n<p>It is the first known member of its group with such a broad resistance profile, suggesting that cold-adapted microbes can act as long-term reservoirs of resistance genes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Antibiotic resistance genes raise new concerns<\/h2>\n\n\n\n<p>Its genome carries more than 100 genes linked to antibiotic resistance and almost 600 genes whose functions scientists still do not understand. Eleven of those appear able to produce compounds that kill or slow other microbes. <\/p>\n\n\n\n<p>In petri dish tests, SC65A.3 even managed to inhibit dangerous <a href=\"https:\/\/www.ecoticias.com\/en\/amazonian-flies-may-be-carriers-of-a-new-bacterium-linked-to-andean-fever\/24780\/\">pathogens<\/a> such as Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae.<\/p>\n\n\n\n<div class=\"gb-element-6d999e61\">\n<div><div class=\"gb-looper-0346c8ab\">\n<div class=\"gb-loop-item gb-loop-item-503c5d5e post-30148 post type-post status-publish format-standard has-post-thumbnail hentry category-science resize-featured-image\">\n<h3 class=\"gb-text gb-text-60c2b3b0\">Read More: <a href=\"https:\/\/www.ecoticias.com\/en\/the-pink-rocks-of-antarctica-reveal-a-gigantic-secret-structure-hidden-under-the-ice-for-175-million-years\/30148\/\">The pink rocks of Antarctica reveal a gigantic secret structure hidden under the ice for 175 million years<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p>Study co-author Cristina Purcarea describes the strain as a double edged discovery, explaining that it \u201cshows resistance to multiple modern antibiotics and carries over 100 resistance related genes\u201d while also displaying enzymatic activities with promising <a href=\"https:\/\/www.ecoticias.com\/en\/goodbye-to-concrete-as-we-know-it-welcome-to-living-bricks-that-repair-themselves\/24667\/\">biotechnological potential<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why antimicrobial resistance in ancient ice matters<\/h2>\n\n\n\n<p>Why does this matter beyond one remote cave most of us will never visit? Because it confirms that <a href=\"https:\/\/www.cdc.gov\/antimicrobial-resistance\/about\/index.html\" target=\"_blank\" rel=\"noopener\">antimicrobial resistance<\/a> evolved naturally in the environment long before humans started prescribing pills and injections, and that ancient ice can store those genes for thousands of years. In a warming world, <a href=\"https:\/\/www.ecoticias.com\/en\/huge-iceberg-breakoff-antarctica\/12912\/\">melting glaciers and permafrost<\/a> could gradually release similar microbes or, more realistically, their DNA into rivers, soils, and modern bacterial communities.<\/p>\n\n\n\n<p>Health agencies are already sounding the alarm. The World Health Organization estimates that bacterial antimicrobial resistance directly caused about 1.27 million deaths in 2019 and contributed to nearly 5 million worldwide. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/www.ecoticias.com\/en\/wp-content\/uploads\/2026\/04\/ancient-bacteria-antibiotic-resistance-romania-ice-cave-1.jpg\" alt=\"Researchers extracting a vertical ice core sample from the frozen floor of a Romanian cave for microbial analysis.\" class=\"wp-image-30384\" title=\"\" srcset=\"https:\/\/www.ecoticias.com\/en\/wp-content\/uploads\/2026\/04\/ancient-bacteria-antibiotic-resistance-romania-ice-cave-1.jpg 1800w, https:\/\/www.ecoticias.com\/en\/wp-content\/uploads\/2026\/04\/ancient-bacteria-antibiotic-resistance-romania-ice-cave-1-300x169.jpg 300w, https:\/\/www.ecoticias.com\/en\/wp-content\/uploads\/2026\/04\/ancient-bacteria-antibiotic-resistance-romania-ice-cave-1-768x432.jpg 768w, https:\/\/www.ecoticias.com\/en\/wp-content\/uploads\/2026\/04\/ancient-bacteria-antibiotic-resistance-romania-ice-cave-1-1536x864.jpg 1536w, https:\/\/www.ecoticias.com\/en\/wp-content\/uploads\/2026\/04\/ancient-bacteria-antibiotic-resistance-romania-ice-cave-1-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\">Scientists isolated the ancient Psychrobacter strain from an ice core representing 5,000 years of environmental history.<\/figcaption><\/figure>\n\n\n\n<p>If antibiotics fail more often, everyday problems such as a urinary tract infection or a minor surgery can become much riskier than most patients expect when they pick up a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ancient microbes could also help fight superbugs<\/h2>\n\n\n\n<p>At the same time, the cave bacterium hints at new tools for fighting back. Its ability to suppress hard to treat \u201c<a href=\"https:\/\/www.ecoticias.com\/en\/these-tiny-creatures-hiding-in-your-garden-could-produce-substances-capable-of-killing-superbugs-in-a-matter-of-seconds\/24996\/\">superbugs<\/a>\u201d and its large set of unknown genes turn the ice core into a kind of natural library for future antimicrobials and industrial enzymes, provided laboratories handle these strains under strict safety rules.<\/p>\n\n\n\n<div class=\"gb-element-1318eb5a\">\n<div><div class=\"gb-looper-eecfecd9\">\n<div class=\"gb-loop-item gb-loop-item-d4ea80b9 post-30161 post type-post status-publish format-standard has-post-thumbnail hentry category-environment resize-featured-image\">\n<h3 class=\"gb-text gb-text-8a58189b\">Read More: <a href=\"https:\/\/www.ecoticias.com\/en\/for-years-no-one-knew-what-those-strange-clay-chimneys-protruding-from-the-ground-in-the-amazon-were-for-until-a-study-published-on-february-23-2026-came-up-with-an-answer-that-was-a\/30161\/\">For years, no one knew what those strange clay \u201cchimneys\u201d protruding from the ground in the Amazon were for, until a study published on February 23, 2026, came up with an answer that was as simple as it was brilliant<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p>In other words, ancient microbes like SC65A.3 are both a warning and a blueprint. As climate change eats away at Earth\u2019s frozen archives, the question is not only what might emerge from the ice, but whether we will have turned that knowledge into smarter antibiotic use and new treatments in time.<\/p>\n\n\n\n<p>The study was published in <a href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2025.1713017\/full\" target=\"_blank\" rel=\"noopener\"><em>Frontiers in Microbiology<\/em><\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What happens when a microbe from 5,000 years ago meets some of the strongest drugs on today\u2019s hospital shelves? In &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"A 5,000-year-old bacterium awakens from the ice in a cave in Romania, revealing something disturbing: it was already resistant to antibiotics still used today to treat serious infections\" class=\"read-more button\" href=\"https:\/\/www.ecoticias.com\/en\/a-5000-year-old-bacterium-awakens-from-the-ice-in-a-cave-in-romania-revealing-something-disturbing-it-was-already-resistant-to-antibiotics-still-used-today-to-treat-serious-infections\/30382\/#more-30382\" aria-label=\"Read more about A 5,000-year-old bacterium awakens from the ice in a cave in Romania, revealing something disturbing: it was already resistant to antibiotics still used today to treat serious infections\">Read more<\/a><\/p>\n","protected":false},"author":15,"featured_media":30383,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"class_list":["post-30382","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","resize-featured-image"],"_links":{"self":[{"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/posts\/30382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/comments?post=30382"}],"version-history":[{"count":1,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/posts\/30382\/revisions"}],"predecessor-version":[{"id":30385,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/posts\/30382\/revisions\/30385"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/media\/30383"}],"wp:attachment":[{"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/media?parent=30382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/categories?post=30382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ecoticias.com\/en\/wp-json\/wp\/v2\/tags?post=30382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}